Mitochondrial division: molecular machinery and physiological functions
نویسندگان
چکیده
منابع مشابه
Molecular machinery of mitochondrial fusion and fission.
Mitochondria generate energy by oxidative phosphorylation; play a crucial role in iron-sulfur cluster assembly; and participate in intermediary metabolism, calcium signaling, and apoptosis. They are bounded by a double membrane and contain 800 (yeast) to 1500 (human) different proteins. Although the vastmajorityofmitochondrial proteins are encoded in thenucleus and post-translationally imported...
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Liposome division by a simple bacterial division machinery.
We previously reconstituted Z rings in tubular multilamellar liposomes with FtsZ-YFP-mts, where mts is a membrane-targeting amphiphilic helix. These reconstituted Z rings generated a constriction force but did not divide the thick-walled liposomes. Here we developed a unique system to observe Z rings in unilamellar liposomes. FtsZ-YFP-mts incorporated inside large, unilamellar liposomes formed ...
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GABA(B) receptors are broadly expressed in the nervous system and have been implicated in a wide variety of neurological and psychiatric disorders. The cloning of the first GABA(B) receptor cDNAs in 1997 revived interest in these receptors and their potential as therapeutic targets. With the availability of molecular tools, rapid progress was made in our understanding of the GABA(B) system. Thi...
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The superfamily of cyclic nucleotide (cN) phosphodiesterases (PDEs) is comprised of 11 families of enzymes. PDEs break down cAMP and/or cGMP and are major determinants of cellular cN levels and, consequently, the actions of cN-signaling pathways. PDEs exhibit a range of catalytic efficiencies for breakdown of cAMP and/or cGMP and are regulated by myriad processes including phosphorylation, cN b...
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ژورنال
عنوان ژورنال: Current Opinion in Cell Biology
سال: 2011
ISSN: 0955-0674
DOI: 10.1016/j.ceb.2011.04.009